First and second trimester prenatal screening update

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP).

This report examines the safety, screening accuracy, therapeutic efficacy, patient outcomes and cost effectiveness of first trimester Quad (1T-Quad) +/- NT and NIPT screening for fetal trisomies.

Section Authors:

  • Section One – Technology Effectiveness and Safety: Ken Bond, Dagmara Chojecki
  • Section Two – Economic Analysis: Charles Yan, Anderson Chuck
  • Information Specialist: Dagmara Chojecki
  • Manuscript Review & Critical Comment: Christa Harstall

Publication Type: Health Technology Assessments /
Systematic Reviews

Year of Publication: 2014

Topics: Health Economics / Healthcare Costs, Maternal and Child Health, Screening

Authors: IHE Institute of Health Economics

ISBN (online): 978-1-926929-36-1

INAHTA URL: and second trimester prenatal screening update.pdf