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The outcome of IHE initiatives is providing better information for developing health policy and best medical practices. IHE disseminates information in many ways. In addition to publications in peer-reviewed journals, IHE produces books and a variety of reports synthesizing information in a particular field.

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Results for: Event Proceedings Backgrounders Books Health Technology Assessments / Systematic Reviews Infectious Diseases Therapy

Endovascular therapy for acute ischemic stroke

August 24, 2017

| IHE Institute of Health Economics

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This STE report examines the social and system demographics, technological safety and therapeutic efficacy/effectiveness, cost-effectiveness, and budget impact of endovascular therapy for acute ischemic stroke, contextualized to the Alberta setting. Section Authors: Section…

Hysteroscopic tubal sterilization

September 30, 2014

| IHE Institute of Health Economics

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report is an evidence assessment of the clinical effectiveness and safety of hysteroscopic tubal sterilization, and the value for money associated with adopting hysteroscopic tubal sterilization in Alberta. Section Authors: Section One – Background and Context: Carmen…

Endovenous Ablation Interventions for Symptomatic Varicose Veins of the Legs

September 30, 2014

| IHE Institute of Health Economics

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report is an evidence assessment of the best available research evidence on the safety and effectiveness, cost effectiveness and budget impact of using Endovenous Laser Ablation (EVLA) or Endovenous Radiofrequency Ablation (RFA) in the management of symptomatic varicose…

Total prosthetic replacement of the temporomandibular joint: a rapid evidence assessment and economic analysis

May 03, 2013

| IHE Institute of Health Economics

This health technology assessment report has been produced in response to a request from Alberta Health (AH) as part of the Alberta Health Technologies Decision Process (AHTDP) to perform an evaluation of the scientific evidence on the safety and effectiveness of TMJ Concepts® and Biomet® Microfixation TMJ prostheses for adults who are indicated for total TMJ replacement.…

Islet transplantation for the treatment of type 1 diabetes

February 13, 2013

| IHE Institute of Health Economics

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report is an update of the 2008 report on islet transplantation (IT) for Type 1 diabetes (T1DM). Section One of this analysis was intended to describe the profile of T1DM (definition, progression, epidemiology, and population dynamics of affected adults in Alberta, in Canada,…

Bariatric treatments for adult obesity

March 20, 2012

| IHE Institute of Health Economics

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report summarizes available key information on the use of bariatric treatments for adult obesity in Alberta and North America (mainly Canada). This analysis was intended to describe the profile of adult obesity (definition, progression, epidemiology, and population dynamics…

Insulin pump therapy for type 1 diabetes

March 20, 2012

| IHE Institute of Health Economics

Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). This report examines the research evidence on the safety and efficacy of insulin pump therapy, as compared to multiple daily insulin injections, in the treatment of children, adults, and pregnant women diagnosed with type 1 diabetes. The report also analyses the economic impact…

Fecal transplantation for the treatment of Clostridium difficile-associated disease or ulcerative colitis

March 01, 2011

| Bing Guo, Christa Harstall, Thanh Nguyen, Arto Ohinmaa

  Alberta STE Report written under contract with the Alberta Health Technologies Decision Process (AHTDP). Fecal transplantation for the treatment of Clostridium difficile-associated disease or ulcerative colitis examines the clinical research evidence on the safety and effects of fecal transplantation in the treatment of patients with Clostridium difficile-associated disease…

Fetal Alcohol Spectrum Disorder: Management and Policy Perspectives of FASD

November 01, 2010

Reflecting the recent increased public awareness of the topic, this is the first and most comprehensive resource for over a decade on the molecular basis, prevalence, treatment options, socioeconomic impact, and prevention strategies of FASD. Edited by world-renowned experts, this compendium includes the latest research results to provide new insights and realistic estimations…

Treatment for Convicted Adult Male Sex Offenders

July 20, 2010

| Paula Corabian, Maria Ospina, Christa Harstall

This health technology assessment report is an overview of systematic reviews reporting on the efficacy/effectiveness of psychotherapy and/or pharmacotherapy interventions delivered within Sex Offender Treatment (SOT) programs to reduce the risk of re-offending in convicted adult male sex offenders. Information Specialist: Liz Dennett

Parkinson Disease: A Health Policy Perspective

April 01, 2010

Part of the successful Institute of Health Economics (IHE) book series, this handbook and ready reference adopts a unique approach in combining policy recommendations with specific treatment options for Parkinson patients. The first part of the book deals with the clinical medical, social and economical aspects of Parkinson Disease. These ten chapters include the latest diagnosis…

Islet Transplantation for the Treatment of Type 1 Diabetes - An update

December 01, 2008

| Bing Guo, Paula Corabian, Christa Harstall

The purpose of this report is to update an earlier HTA report published in 2003. This report examines the newly published clinical research evidence on the safety and efficacy/effectiveness of islet transplantation in type 1 diabetic patients who have severe hypoglycemia episodes or hyperglycemia unawareness but are without kidney failure. The main clinical efficacy/effectiveness…

Chronic Pain: A Health Policy Perspective

September 01, 2008

Discussing all aspects of chronic pain management, this is the second volume of the new book series on health care and disease management, published with the Institute of Health Economics (IHE) in Edmonton, Canada. The authors provide an introduction into the history, pathophysiology, ethics and epidemiology of chronic pain before covering the different aspects of treating chronic…

Evidence of Benefits from Telemental Health: A Systematic Review

October 13, 2007

| David Hailey, Risto Roine, Arto Ohinmaa

Evidence of benefit from telemental health applications: a systematic review. This review considers the evidence of benefit from use of telemental health (TMH) in studies that had clinical, economic, or administrative outcomes. The review also includes studies that provided information on the accuracy or feasibility of TMH. Information Specialist: Janice Varney

Gastric Electrical Stimulation (EnterraTM Therapy system) for the Treatment of Gastroparesis

January 01, 2006

| Carmen Moga, Christa Harstall

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #37. The aim of this paper is to present the current evidence on the efficacy/effectiveness, safety, and efficiency of gastric electrical stimulation (EnterraTM Therapy System) used for the treatment of patients with severe gastroparesis (GP). Information Specialist: Liz Dennett NOTE: In 2006 the Alberta Heritage…

Trigger Point Injections for Chronic Non-malignant Musculoskeletal Pain

January 01, 2005

| Ann Scott, Bing Guo

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #35. The objective of this report is to assess the efficacy and safety of using trigger point injection (TPI) to treat patients with chronic non-malignant musculoskeletal pain, based on a systematic review of the current published evidence, and to determine the current state of the procedure, the feasibility of…

Ovulation Induction Drug Therapy for Anovulatory Infertility Associated with Polycystic Ovary Syndrome

March 01, 2004

| Paula Corabian, Ann Scott

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #33. This report is a systematic review and critical appraisal of the evidence on the use of ovulation induction (OI) drug therapy to manage anovulatory infertility associated with polycystic ovary syndrome (PCOS) in women of reproductive age. The aim was to provide the current published scientific evidence about…

Surgical Treatments for Deep Venous Incompetence

July 01, 2003

| Ann Scott, Paula Corabian

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #32. The aim of this report was to critically appraise and synthesise the published evidence regarding the short- and long-term efficacy/effectiveness of surgical techniques for patients with deep venous incompetence, and attendant skin changes/ulceration, that is refractory to standard care. Information Specialist:…

Islet Cell Transplantation for the Treatment of Non-uremic Type 1 Diabetic Patients with Severe Hypoglycemia

April 01, 2003

| Bing Guo, Christa Harstall, Paula Corabian

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #31. This report was prepared in response to a request from Alberta Health and Wellness (AHW) for information about the use of islet cell transplantation for patients with type 1 diabetes. AHW was specifically interested in the current status of islet cell transplantation using the Edmonton protocol for a sub-population…

Multidisciplinary Pain Programs for Chronic Pain: Evidence from Systematic Reviews

January 01, 2003

| Maria Ospina, Christa Harstall

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #30. Using the 1996 National Population Health survey data, this report provides an estimate of the prevalence of chronic pain (CP) among Albertans. It was estimated that 11.2% of Albertans suffer some level of CP and about 2.3% suffer from severe CP. As the proportion of individuals suffering from CP increases…

Acupuncture: Evidence from Systematic Reviews and Meta-analyses

March 01, 2002

| Patricia Leggett Tait, Laurie Brooks, Christa Harstall

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #27. This project is Part II of a request from several Regional Health Authorities and Alberta Health and Wellness, regarding two key objectives: to present information on the regulation of acupuncture in Alberta, including the scope of practice and coverage of services; and to conduct a systematic review of current…

Vagus Nerve Stimulation for Refractory Epilepsy

March 01, 2001

| Paula Corabian, Patricia Leggett Tait

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #24. This report has been produced in response to a request from Alberta Health and Wellness for an update on the use of vagus nerve stimulation (VNS) for refractory epilepsy. The intent was to inform health policy makers, medical practitioners, and the public on the current status of the use of VNS for refractory…

Allogeneic stem cell transplantation methods

January 01, 2000

| Philip Jacobs, David Hailey, Nadine MacLean

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #18. This report has been prepared following interest by the Alberta Cord Blood Bank in obtaining advice on the comparative effectiveness and costs of different types of stem cell transplantation. Earlier assessments by the Foundation have considered peripheral blood stem cell transplantation and cord blood transplantation.…

Brachytherapy for prostate cancer

December 01, 1999

| Fiona Wills, David Hailey

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #17. The present report has been prepared as a follow up to the previous assessment because of continued interest in the technology by the health ministry and others. It considers studies that have been reported in the literature since completion of the earlier assessment (1997-1999) and focuses on the efficacy…

Low level laser therapy for wound healing

October 01, 1999

| Wendy Schneider, David Hailey

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #19. A request for information about the use of low level laser therapy (LLLT) to assist wound healing was received from the Capital Health Authority (CHA). This technology has been increasingly used within the Edmonton area, with somewhat different approaches being taken by individual operators. The concern was…

Treatment Options for Acoustic Neuroma

July 01, 1999

| Wendy Schneider, David Hailey

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #15. The present health technology assessment report has been prepared following a request by Alberta Health and Wellness for additional information on the use of stereotactic radiosurgery (SRS) in the treatment of acoustic neuroma, one of the applications considered in an earlier publication on SRS. Two main issues…

Intraocular Lenses for uncomplicated senile cataracts

June 01, 1999

| Christa Harstall, Wendy Schneider

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #14. This report has been prepared because of the interest by the Consumers' Association of Canada and the Health Ministry in the increasing use of newer types of intraocular lenses (IOLs) and in their comparative advantage. The focus of the report is on the safety, efficacy and effectiveness of the three types…

Cord Blood Transplantation

December 15, 1998

| Maureen Yunkap Kwankam, David Hailey, Philip Jacobs

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #13. This assessment has been prepared in view of the interest at the University of Alberta Hospital in developing a cord blood banking facility in the province and to provide information to decision makers on the current status of cord blood transplantation (CBT). The principal purpose of the assessment was to…

Hyperbaric oxygen treatment in Alberta

April 01, 1998

| Craig Mitton, David Hailey

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #8. This report has been prepared to provide information to health authorities and others on the available evidence on effectiveness of HBOT and the possible economic impact on health care should a second HBO facility be established in the province. Issues addressed in the report include: Whether HBOT has been…

Stereotactic radiosurgery: options for Albertans

March 01, 1998

| Wendy Schneider, David Hailey

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #9. The present report has been prepared following a request by Alberta Health in relation to referral of patients outside the province for treatment with stereotactic radiosurgery (SRS). There was interest by the department in the comparative effectiveness of the two main approaches to SRS (GK and LINAC) and in…

Dynamic posturography in the rehabilitation of stroke, brain injured and amputee patients

February 01, 1998

| Christa Harstall

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #7. This assessment was undertaken at the request of a Regional Health Authority to provide input into a funding decision on a computerized dynamic posturography (CDP) system for use by a rehabilitation department. The focus of this study was restricted to the clinical use of CDP by the rehabilitation community.…

Computerized gait analysis in the rehabilitationof children with cerebral palsy and spina bifida

October 01, 1997

| Jo-Anne Tomie, David Hailey

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #5. This assessment of computerized gait analysis in the management of children with cerebral palsy (CP) or spina bifida (SB) has been prepared at the request of the Glenrose Hospital, Edmonton. The hospital has already undertaken developmental work towards establishing a gait analysis facility. Advice was sought…

In vitro fertilization and embryo transfer as a treatment for infertility

March 01, 1997

| Paula Corabian

Alberta Heritage Foundation for Medical Research (AHFMR) HTA Report #3. The intent of this report is to inform medical practitioners and the public on the current status of in vitro fertilization and embryo transfer (IVF-ET) as a treatment for various types of infertility, and on its use and coverage in Canada. The report has been prepared because of the interest and debate regarding…

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